LittleOne - including its embedded Sequencer and Trancegate modules - feature a solid, sample-based timing accuracy with Hosts and DAWs sequencers.
By the way many external factors (e.g., audio devices using unconventional buffer sizes, the use of 32-bit to 64-bit bridges and wrappers, etc.)
could lead to some timing inaccuracies (it could happen mostly with previous versions of Image-Line FLStudio, since it uses a wrapper for plugins, no other
Hosts or DAWs seem to be affected). By the way, this can be easily fixed: the first way to do it is specific to Image-Line FLStudio Host / DAW,
the second could be applied to any Host / DAW.
First Way : changing the settings in the FLStudio VSTi-wrapper
In the VSTi-wrapper select :
Adv. Settings [Cogwheel Icon] -> Processing [Tab] -> Opt. -> Use fixed size buffers [Activate]
Second Way : forcing notes to retrig
This scenario produces the retrig issue (bad Host syncing)
Just end a note before the next one starts to avoid the retrig issue